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Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease with primary manifestation in the joints. Early management of RA will prevent further joint damage. The joint damages, result of uncontrolled disease activity, will decrease patientâ€™s quality of life.
RA should be diagnosed earlier and followed by early treatment initiation, in order to prevent further damages. This study aimed to determine the pattern of joint involvement in RA in order to made earlier diagnosis and treatment initiation.
Method: This research was conducted using descriptive study design. Data were obtained using interview of RA patients who coming to Rheumatology Clinic of Dr. Hasan Sadikin General Hospital from August 2016 to October 2016. Collected data included number of joints involvement, duration of therapy, and duration of illness after diagnosed according to the criteria of ACR / EULAR 2010.
Result: Ninety-seven RA patients were involved in this study. Subjects were dominantly women (87%), the highest age group was 45-49 years old (17.53%), duration of the disease <5 years (90.72%), and duration of therapy > 3 months (86%). Joint that frequently involved at the time when the diagnosis made was first proximal interphalangeal (49.50%), overall findings during the course of RA was the wrist joint (90.72%).
There were different tendency of joint involvement between the gender, knee joints occured in 53,84% male subjects, while PIP joints were accounted for 52,38% in
Conclusion: The first PIP was the most common joint involved in RA patients when the diagnosis made. The wrist joint involvement was dominantly found in overall course of RA. Knee joint involvement was majorly found in male RA patients, whereas female RA patients would suffer mostly from PIP joint involvement.
Keywords: involvement pattern, joints, rheumatoid arthritis
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- Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO, et al. 2010 Rheumatoid Arthritis Classification Criteria. Arthritis Rheum. 2010;62(9):2569â€“81.
- Kaneko Y, Takeuchi T. A Paradigm Shift in Rheumatoid Arthritis over the Past Decade. Intern Med. 2014;53:1895â€“903.
- Papana A, Meng SJ, Wei YX, Wang W, Ruth M, Page C, et al. Prevalence of rheumatoid arthritis in low â€“ and middle â€“ income countries : A. J Glob Health. 2015;5(1):1â€“10.
- A. Gibofsky, MD, JD, FACP F. Overview of Epidemiology, Pathophysiology, and Diagnosis of Rheumatoid Arthritis. Am J Manag Care. 2010;18(13):295â€“302.
- Kay J, Upchurch KS. ACR / EULAR 2010 rheumatoid arthritis classification criteria. Rheumatology. 2012;51:5â€“9.
- Monti S, Montecucco C, Bugatti S, Caporali R. Rheumatoid arthritis treatment : the earlier the better to prevent joint damage. Rheum Musculoskelet Dis. 2015;1(1):1â€“5.
- Heidari B. Rheumatoid Arthritis : Early diagnosis and treatment outcomes. Casp J Intern Med. 2011;2(1):161â€“70.
- Demoruelle MK, Deane KD. Treatment Strategies in Early Rheumatoid Arthritis and Prevention of Rheumatoid Arthritis. Curr Rheumatol Rep. 2013;14(5):472â€“80.
- Nagano J, Sudo N, Nagaoka S, Yukioka M, Kondo M. Life events, emotional responsiveness, and the functional prognosis of patients with rheumatoid arthritis. Biopsychosoc Med. 2015;9(15):1â€“7.
- Nell VP, Machold KP, Eberl G, Stamm TA, Uffmann M, Smolen JS. Benefit of very early referral and very early therapy with disease-modifying antirheumatic drugs in patients with early rheumatoid arthritis. Rheumatology (Oxford). 2004; 43:906â€“14.
- Iskandar A, Wachjudi RG. Diagnosis dan Prinsip Penatalaksanaan Artritis Reumatoid: Himpunan Makalah Lengkap Reumatologi Klinik Bandung. Bandung: Pusat Informasi Ilmiah, Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran UNPAD, RS Dr Hasan Sadikin; 2014: p.309-40
- Shah A, William E. Rheumatoid Arthritis. In: Kasper D, Fauci A, Hauser S, Longo D, Jameson J, Loscalzo J, editors. Harrisonâ€™s principles of internal medicine. 19th ed. New York: McGraw - Hill Education; 2015, p2136-49